PESA and TESA
A fine needle draws sperm without an incision, when the route out is blocked.
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A diagnosis of azoospermia is not the end of the road to biological fatherhood. Assoc. Prof. Tuncay Taş performs microsurgical testicular sperm extraction in Istanbul, working directly with your embryology team on the day.
Micro TESE, or microsurgical testicular sperm extraction, looks for sperm directly inside the testicle when none is found in the ejaculate, for men with non obstructive azoospermia where the testicle itself produces little or no sperm. This differs from a varicocele, a common and often correctable cause of reduced sperm production that is usually ruled out or treated first.
An operating microscope lets the surgeon identify and sample only the tubules most likely to contain sperm, removing less tissue than older, unguided TESE. This is linked to higher retrieval rates and lower risk. Any sperm found is used with ICSI as part of an IVF cycle.
Considered once azoospermia has been confirmed and worked up properly.
No sperm found on two separate semen analyses
A suspected or confirmed non obstructive azoospermia
Hormones showing reduced testicular sperm production
A genetic finding, such as Klinefelter syndrome
The right technique depends chiefly on whether sperm production is blocked or reduced at the source.
A fine needle draws sperm without an incision, when the route out is blocked.
Random samples without microscopic guidance, removing more tissue for a lower success rate.
A microscope identifies the tubules most likely to contain sperm — the technique of choice here.
Retrieval is timed to your partner’s IVF cycle where possible, with extra sperm frozen for future attempts.
Tick what you already have. Nothing here is submitted or saved, it is just for you.
Do you have: Two separate semen analyses confirming azoospermia?
Do you have: Hormone panel: FSH, LH and testosterone?
Do you have: Karyotype (chromosome) test?
Do you have: Y chromosome microdeletion test?
Do you have: Scrotal ultrasound?
Do you have: Partner’s fertility assessment?
A proper diagnosis comes before any operation, so the workup is thorough.
Two analyses confirming azoospermia are needed before a surgical plan is discussed.
FSH, LH, testosterone, karyotype and Y chromosome microdeletion tests help predict the chance of finding sperm.
Timing is coordinated with your partner’s egg collection so retrieval happens when fresh sperm is needed.
Under general, spinal or regional block anaesthesia, with an embryologist present.
A short checklist covered in full at your consultation.
Stop smoking at least two weeks before surgery
Tell the team about any blood thinners or aspirin you take
Follow the fasting instructions for the night before
Bring your hormone, genetic and semen analysis results
Pick one option in each category for an instant estimate. This is a planning figure, not a quote.
Base package: Micro TESE surgery (included in every estimate)
Suggested trip length: 5 to 7 days, covering assessment, surgery and clearance to fly.
Micro TESE has a strong safety record. These are discussed with every patient beforehand.
Bleeding or a scrotal haematoma, uncommon and usually minor
Infection, reduced by antibiotics given around the time of surgery
A temporary drop in testosterone, checked at your follow up
Anaesthesia carries its own small risks, discussed beforehand
The operation is a single day, but the weeks after protect the result and your comfort.
Most men go home the same day or next morning, wearing a light dressing and scrotal support.
You rest, avoid heavy lifting or exercise, and let swelling settle before your follow up clears you.
A follow up hormone check reviews testosterone. If sperm was frozen, your fertility clinic is informed of next steps.
Report increasing pain, fever, swelling or discharge right away
Follow up continues by video call once you are home
Indicative packages in Istanbul against typical private pricing in the US, UK and Western Europe. Your exact quote follows your workup review.
| Package | Dr. Tuncay Taş Istanbul, Turkey | United States | United Kingdom | Western Europe |
|---|---|---|---|---|
| Micro TESE surgerySurgical fee, anaesthesia, embryology support | $3,000 – $4,500 | $8,000 – $15,000 | £4,000 – £7,000 | €5,000 – €9,000 |
| Sperm cryopreservationFirst year of storage | $300 – $500 | $1,000 – $1,500 | £500 – £800 | €600 – €900 |
These are indicative planning ranges, not a quote, and cover the surgical procedure only; IVF and ICSI are priced separately by your fertility clinic.
Surgeon and embryology fees
Hospital stay and anaesthesia
Airport transfers and an interpreter
Video follow up after you fly home
Micro TESE rewards surgical experience and close coordination with embryology more than almost any other andrology procedure.
Assoc. Prof. Tuncay Taş performs andrology microsurgery regularly and has trained many andrologists. Read more about his background and training.
An embryologist is on site so you know if sperm was found before you leave.
Fertility treatment is time sensitive, tied to your partner’s cycle and age. Surgery can be arranged within weeks once workup is done.
The same operation costs considerably less in Istanbul than in the US, UK or Western Europe.
Micro TESE uses an operating microscope to identify the tubules most likely to contain sperm, removing less tissue for a better success rate than conventional TESE.
Published series report retrieval rates of 40 to 60 per cent for non obstructive azoospermia, varying by underlying cause.
The cost covers the surgical procedure, anaesthesia, hospital stay and embryology support, well below equivalent US, UK or Western European pricing. Contact us for a personalised quote after your workup review.